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Cheesy Alfredo Hamburger Casserole

Casserole dish of Cheesy Alfredo Hamburger Casserole made with Prego® sauce
  • prep time: 15 min
  • total time: 40 min
  • serves: 6 people
  • calories: 458 1 serving

This family-friendly casserole is ready in less than an hour. Ground beef, creamy pasta sauce and tomatoes are topped with buttermilk biscuits and baked to golden brown deliciousness.


  • 1 1/2 pounds ground beef
  • 1 jar (14.5 ounces) Prego® Homestyle Alfredo Sauce
  • 1 medium tomato, chopped (about 1 cup)
  • 1 tablespoon Worcestershire sauce
  • 1/2 cup shredded Cheddar cheese or mozzarella cheese
  • 1 package (7.5 ounces) refrigerated biscuit dough (10 biscuits)


  • Tips

    • For Creamy Mushroom Burger Bake, stir 1/2 cup leftover cooked mushrooms into the cooked beef mixture before baking.  Or you can use other cooked vegetables, like corn or peas.
    • Ingredient Note: You can also use a 12-ounce package of refrigerated biscuit dough (12 biscuits) in this recipe.
  • Step 1

    Heat the oven to 400°F.

  • Step 2

    Cook the beef in a 12-inch skillet over medium-high heat, stirring often to separate meat.  Pour off any fat.

  • Step 3

    Stir in the sauce, tomato and Worcestershire and heat to a boil.  Reduce the heat to low.  Cook for 5 minutes.  Spoon the beef mixture into a 1 1/2-quart casserole.  Sprinkle with the cheese.  Arrange the biscuits on the beef mixture.

  • Step 4

    Bake for 10 minutes or until the biscuits are golden brown.

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Made With

Calories 458
Total Fat 28 g
Sat. Fat 11.6 g
Trans Fat 1 g
Cholesterol 112 mg
Sodium 947 mg
Total Carb 21 g
Dietary Fiber 0 g
Sugar 4 g
Protein 28 g
Vitamin D 0 %DV
Calcium 12 %DV
Iron 15 %DV
Potassium 10 %DV

This nutritional information refers to each serving of the entire recipe and not just the products used as ingredients.